Pathology

Pathology is a branch of medical science primarily concerning the cause, origin and nature of disease. It involves the examination of tissues, organs, bodily fluids and autopsies in order to study and diagnose disease.

Currently, pathology can be divided into eight main areas, depending on the types of methods used or the types of diseases examined. These different disciplines are described below.

General pathology

General pathology describes a complex and broad field that involves the study of the mechanisms behind cell and tissue injury, as well as understanding how the body responds to and repairs injury. Examples of areas that may be studied include necrosis, neoplasia, wound healing, inflammation and how cells adapt to injury. Thorough understanding in these areas is applied in the diagnosis of disease. General pathology is also the term used to describe anatomical and clinical pathology.

This field covers areas of pathology, but at a less specialist level. A person working in general pathology would be trained in the areas of laboratory analysis, such as hematology and clinical chemistry. However, they would have a less detailed knowledge than a person who specializes in one of these fields.

Anatomical pathology

This field is concerned with the study and diagnosis of illness through microscopic analysis of samples from bodily fluids, tissues organs and sometimes the entire body or autopsy. Factors that may be examined include the cell appearance, anatomical make up and chemical signatures within cells.

This discipline can be subdivided into several disciplines and examples of these are given below:

Histology – Samples of bodily tissues and organs are prepared and examined in order to detect and diagnose disease. The architecture of tissue is observed at a microscopic level and the relationship between different cell and tissue types is examined.
Cytology – Bodily fluids and tissues are examined at the cellular level in order to screen for and diagnose disease and help aid treatment decisions. A cytologist will examine how cells look, form and function.
Forensic pathology – Forensic pathology is the examination of an autopsy in order to discover the cause of death. The external appearance is first assessed to check for evidence of wounds or suffocation, for example. Surgical procedures are then begun and the internal organs are studied to see whether internal injuries exist and are connected to external ones.

Clinical pathology

Also referred to as laboratory medicine, clinical pathology concerns the analysis of blood, urine and tissue samples to examine and diagnose disease. Examples of the information clinical pathology laboratories may provide include blood count, blood clotting and electrolyte results. A clinical pathologist is usually trained in microbiology, hematology or blood banking, but not at the same expert level as someone who specializes in one of these fields.

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